Central to the success of DES has been the use of a polymer coating ... drug. However, the permanent polymers in first-generation sirolimus- and paclitaxel-eluting stent platforms used to control ...

Drug-eluting stents are widely used to mitigate ... To overcome these limitations, research into coating stent surfaces with bioactive molecules like proteins or nucleic acids is ongoing.

Purpose: The mechanism of action and pharmacokinetics of sirolimus when used as part of a drug-eluting stent (DES) and the efficacy and cost of using DESs versus bare-metal stents are discussed.

The drug-eluting stent is an example of a drug–device combination ... which are often toxic. Coating potentially dangerous nanoparticles and quantum dots with biocompatible materials could ...

Boston Scientific markets a broad portfolio of internally-developed and self-manufactured drug eluting ... Stent System featuring an ultra-thin abluminal (outer) bioabsorbable polymer coating.