Researchers at Kumamoto University have successfully executed a practical trial of a new genome-editing technique that allows ...

Gene knockout approaches completely ablate gene expression at the DNA level. 3 Researchers can accomplish this by using genome editing tools, such as zinc finger nucleases (ZFN), transcription ...

The malaria parasite is still killing almost half a million people every year. A project has now identified a gene that holds ...

Both gene knockout and knock-in models are powerful tools widely used in biomedical research to gain important insights into ...

However, because so many mouse genes are similar to human genes, geneticists can generate knockout mice in which the mouse counterpart of a human gene of interest is deleted or disrupted.

When the monkeys were single-celled embryos, scientists had used CRISPR editing tools to silence, or “knock out”, a gene that ...

Synthego, a leading genome engineering solutions company, today announced the launch of the Gene Knockout Kit v2. This is the only product that leverages a novel bioinformatics- powered multi-guide ...

Mayo Clinic's Precision Mouse Engineering Core in Minnesota can construct gene-targeted vectors for mice to assist researchers.

To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene of interest. This may be done by deleting portions of the gene's DNA sequence to make it nonfunctional ...

This study presents an enhanced nuclease prime editor (uPEn) that significantly improves gene knock-in and knockout ...

Mayo Clinic's Precision Mouse Engineering Core in Minnesota makes embryonic stem (ES) cell-based gene-targeted mice available to researchers.