Immunotherapy, which uses programmed immune cells to selectively destroy cancer cells, has transformed cancer treatment.

Video of a cytotoxic lymphocyte killing a cancer cell. When the cancer cell is 'hit' it uptakes red dye PI and then the cancer cell undergoes apoptosis. Disclaimer: AAAS and EurekAlert!

The main populations of lymphocytes are B cells, T cells and natural killer (NK) cells. They are typically (although not exclusively) associated with adaptive immune responses. Populations of ...

The cell type, CD8 + cytotoxic T lymphocytes that express a transcription factor called ZNF683/Hobit at high levels, appear to coordinate with other immune cells to expand and attack leukemia cells.

CAR T-cell therapies have demonstrated efficacy in treating blood cancers but, so far, their safety and effectiveness in ...

A team of researchers from the Sant Pau Research Institute (IR Sant Pau) has published a study in the Journal of ...

Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.

Researchers have identified the transfer of mitochondria with mutated DNA from cancer cells to immune cells as a key ...