An Upstate teenager is in custody after being accused of killing her own brother. The Anderson County Sheriff’s Office says ...

The cause of the fire is unknown, but there were reports of possible explosions inside the house, fire officials said.

President Donald Trump quickly signed off on executive orders on Monday, his first day in the Oval Office. He also pardoned ...

The Corrections Department tells NBC5 that 3 correction officers and two nurses became ill after interacting with an ...

Stand still long enough in the Upstate and a Carolina wren might nest in your pocket. It’s maybe a slight exaggeration, but ...

Rep. Andy Ogles (R-Tenn.) proposed an amendment to the U.S. Constitution that would allow President Trump to serve a third ...

No goats were injured after firefighters responded to a fire at a goat barn on Saturday morning. At 9:25 a.m., the Townville ...

"Paws Allen" is a rescue pup from Buffalo, NY in the 2025 Puppy Bowl. Viewers can vote daily for Paws Allen to be the Most ...

Spartanburg’s 8 percent jump in real estate closings was the 2nd-largest in the state in 2024, behind the Aiken area, ...

FARMVILLE, Va. (AP) — Michael Christmas had 17 points in Longwood's 80-54 victory over South Carolina Upstate on Saturday.

Less than an inch of snow fell across Upstate South Carolina, closing schools, businesses and community organizations as ...