Surprise finding sheds light on what causes Huntington's disease, a devastating fatal brain disorder
Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the brain to break down and die.
Brain changes in Huntington's disease decades before diagnosis will guide future prevention trials
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's disease,
New findings shed light on cause of Huntington's disease progression
A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over time, but doesn't start causing harm until it hits a toxic threshold that rapidly leads to the nerve cell’s death.
Early brain changes in Huntington’s disease detected two decades before symptoms
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's disease,
Study finds surprising way that genetic mutation causes Huntington's disease, transforming understanding of the disorder
Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding of the fatal neurodegenerative disorder and suggest potential ways to delay or even prevent it.
Study Unveils Surprising Cause of Brain Cell Death in Huntington's Disease
Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.
New Research Sheds Light on the Causes of Huntington’s Disease
If you’ve ever heard of Huntington’s disease, you know how devastating it can be. This hereditary brain disorder slowly robs people of their ability to think, move, and even communicate. The disease’s progression is relentless,
Medical mystery solved: Why do some people develop Huntington's earlier than others?
New genetic research shows why some people develop deadly Huntington's disease earlier than others. The findings could lead ...
The Economist2d
A better understanding of Huntington’s disease brings hope
But Huntington’s second, self-preserving, oddity is that unlike most genetic disorders it rarely manifests until well into ...
Harvard Medical School2d
New Understanding of How Genetic Mutation Causes Huntington’s Disease
Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though ...
Experts hail 'milestone' in study of the deadly Huntington's disease
About 2,000 people in Australia are affected by Huntington's disease, a fatal and incurable condition that affects the ...
GEN1d
Groundbreaking Huntington Study Reveals Somatic DNA-Repeat Expansion
Published in Cell, the study titled, “Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease,” ...
AL DA News3d
Unveiling Image of Never-Before-Seen Features of a Neuronal Disease
Researchers have mapped the unique structure of protein clusters in Huntington's disease, paving the way for improved ...
BioWorld1d
Huntington’s neurodegeneration starts at 150 repeat expansions
Having 35 copies of the CAG triplet in the gene that causes Huntington’s disease is not a problem. Inheriting 40 could be a ...
STAT2d
Studies reveal a new biology of Huntington’s, renewing drugmaker interest in therapies
A new study highlights the potential of a therapeutic strategy focused on stopping or slowing Huntington's disease.